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Company ReportsAkebia Therapeutics

Akebia Therapeutics(AKBA)

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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Fexeric	Ferric pyrophosphate citrate	2015-09-23		—
Vafseo	Vadadustat	2023-04-24		Chronic renal insufficiency , Anemia

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

drug interactions

,

,

hepatic insufficiency

,

pharmacokinetics

,

chronic kidney failure

,

,

chronic renal insufficiency

,

kidney diseases

,

renal insufficiency

,

disseminated intravascular coagulation

,

venous thromboembolism

,

thromboembolism

,

,

critical illness

,

gastrointestinal hemorrhage

,

drug interactions

healthy volunteers/patients

,

,

subarachnoid hemorrhage

,

,

von willebrand diseases

,

ulcerative colitis

,

hodgkin disease

,

,

cytomegalovirus

,

,

primary myelofibrosis

,

,

precocious puberty

,

type 2 diabetes mellitus

,

healthy volunteers/patients

,

,

central nervous system neoplasms

,

nephrotic syndrome

,

laryngeal diseases

,

,

chronic hepatitis

,

,

,

esophageal neoplasms

,

postmenopausal osteoporosis

,

,

irritable bowel syndrome

,

pathologic dilatation

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

choroid plexus neoplasms

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

hypertrophic pyloric stenosis

,

ganglioneuroblastoma

,

phenylketonurias

,

neuroendocrine tumors

,

b-cell lymphoma marginal zone

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

autism spectrum disorder

,

drug hypersensitivity

,

renal cell carcinoma

,

,

,

squamous cell carcinoma of head and neck

,

b-cell lymphoma

,

head and neck neoplasms

,

squamous cell carcinoma

,

large b-cell lymphoma diffuse

,

pancreatic ductal carcinoma

,

,

,

uveal neoplasms

,

,

mantle-cell lymphoma

,

multiple myeloma

,

myocardial infarction

,

kidney neoplasms

,

hereditary sensory and autonomic neuropathies

,

myelodysplastic syndromes

,

endometrial neoplasms

,

bronchiolitis obliterans syndrome

,

coronary artery disease

,

hypersensitivity

,

philadelphia chromosome

,

lymphoid leukemia

,

,

squamous cell neoplasms

,

waldenstrom macroglobulinemia

,

myeloid leukemia acute

,

castration-resistant prostatic neoplasms

,

hypertrophic cardiomyopathy

,

acute coronary syndrome

,

myocardial ischemia

,

unstable angina

,

margins of excision

,

gouty arthritis

,

gastrointestinal stromal tumors

,

,

,

retinitis pigmentosa

,

,

,

,

,

portal hypertension

,

atopic dermatitis

,

,

,

,

peritoneal neoplasms

,

intestinal obstruction

,

invasive hydatidiform mole

,

central serous chorioretinopathy

,

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

hodgkin disease

,

type 1 diabetes mellitus

,

,

neurofibrosarcoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

netherton syndrome

,

,

eosinophilic esophagitis

,

,

systemic mastocytosis

,

mast-cell leukemia

,

,

,

female infertility

,

sickle cell anemia

,

streptococcus agalactiae

,

angioid streaks

,

pseudoxanthoma elasticum

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

diffuse scleroderma

,

immune system diseases

,

t-cell lymphoma

,

malignant mesothelioma

,

lymphatic diseases

,

immunoproliferative disorders

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

,

myeloid leukemia

,

triple negative breast neoplasms

,

,

prostatic neoplasms

,

follicular lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

non-hodgkin lymphoma

,

cardiovascular diseases

,

hypercholesterolemia

,

graft vs host disease

,

,

psoriatic arthritis

,

,

rheumatoid arthritis

,

meningococcal meningitis

,

meningococcal infections

,

neoplasms by site

,

rectal neoplasms

,

osteitis deformans

,

,

degenerative myopia

,

stomach neoplasms

,

,

neoplasms by histologic type

,

inferior wall myocardial infarction

,

,

psychology rejection

,

organ transplantation

,

graft rejection

,

adenocarcinoma of lung

,

,

aplastic anemia

,

,

carcinoid tumor

,

,

chronic hepatitis c

,

lupus nephritis

,

,

colonic neoplasms

,

retinopathy of prematurity

,

polycythemia vera

,

male breast neoplasms

,

,

,

,

lymphoproliferative disorders

,

hematologic neoplasms

,

left ventricular dysfunction

,

st elevation myocardial infarction

,

non-st elevated myocardial infarction

,

,

,

,

infectious skin diseases

,

soft tissue infections

,

,

malignant carcinoid syndrome

,

serotonin syndrome

,

erectile dysfunction

,

peanut hypersensitivity

,

allergic rhinitis seasonal

,

,

,

haemophilus infections

,

,

cerebrotendinous xanthomatosis

,

,

muscular diseases

,

muscular atrophy

,

spinal muscular atrophy

,

x-linked bulbo-spinal atrophy

,

neovascular glaucoma

,

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

chronic obstructive pulmonary disease

,

,

alpha 1-antitrypsin deficiency

,

primary myelofibrosis

,

progressive supranuclear palsy

,

pick disease of the brain

,

,

breast neoplasms

,

,

macular degeneration

,

,

,

,

kidney transplantation

,

vision disorders

,

choroidal neovascularization

,

type 2 diabetes mellitus

,

neoplasm metastasis

,

retinal vein occlusion

,

chronic urticaria

,

diabetes mellitus

,

liver transplantation

,

essential hypertension

,

multiple sclerosis

,

diabetic retinopathy

,

kidney diseases

,

brain neoplasms

,

relapsing-remitting multiple sclerosis

,

metabolic syndrome

,

renal insufficiency

,

,

pancreatic neoplasms

,

,

chronic kidney failure

,

,

retinal diseases

,

systolic heart failure

,

,

insulin resistance

,

,

geographic atrophy

,

parkinson disease

,

diastolic heart failure

,

chronic renal insufficiency

,

,

diabetic nephropathies

,

wet macular degeneration

,

,

,

retinal neovascularization

,

polypoidal choroidal vasculopathy

,

liver cirrhosis

,

,

diabetes complications

,

isolated systolic hypertension

,

systolic murmurs

,

left ventricular hypertrophy

,

,

glucose intolerance

,

,

chronic progressive multiple sclerosis

,

membranous glomerulonephritis

,

,

,

pathologic neovascularization

,

tick-borne encephalitis

,

,

,

,

renal replacement therapy

,

,

prehypertension

,

,

staphylococcal skin infections

,

,

,

neurobehavioral manifestations

,

heart transplantation

,

pituitary acth hypersecretion

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

,

pituitary neoplasms

,

,

sexual infantilism

,

heart-lung transplantation

,

,

coronavirus infections

,

polyomavirus infections

,

retinal detachment

,

atrial fibrillation

,

iga glomerulonephritis

,

focal segmental glomerulosclerosis

,

nephrosclerosis

,

allergic conjunctivitis

,

reperfusion injury

,

delayed graft function

,

food hypersensitivity

,

islet cell adenoma

,

metabolic bone diseases

,

cryopyrin-associated periodic syndromes

,

,

,

,

immunosuppression therapy

,

angina pectoris

,

microvascular angina

,

spinal muscular atrophies of childhood

,

hematopoietic stem cell transplantation

,

secondary prevention

,

glomerulonephritis

,

chronic renal insufficiency

,

chronic kidney failure

,

kidney diseases

,

,

large b-cell lymphoma diffuse

,

diabetes mellitus

,

diabetic retinopathy

,

diabetic nephropathies

,

kidney diseases

,

,

type 2 diabetes mellitus

,

chronic renal insufficiency

,

,

focal segmental glomerulosclerosis

Globulin, immune

rectal neoplasms

,

ovarian epithelial carcinoma

,

b-cell lymphoma marginal zone

,

colonic neoplasms

,

intestinal neoplasms

,

hematologic diseases

,

myeloid leukemia

,

myelomonocytic leukemia juvenile

,

,

laryngeal diseases

,

,

liver neoplasms

,

alveolar soft part sarcoma

,

,

healthy volunteers/patients

,

,

,

,

esophageal neoplasms

,

,

,

clear cell adenocarcinoma

,

,

thymus neoplasms

,

,

central nervous system neoplasms

,

biphenotypic leukemia acute

,

burkitt lymphoma

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

digestive system diseases

,

colonic diseases

,

autism spectrum disorder

,

drug hypersensitivity

,

colorectal neoplasms

,

renal cell carcinoma

,

triple negative breast neoplasms

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

alzheimer disease

,

multiple myeloma

,

kidney neoplasms

,

,

multiple sclerosis

,

plasma cell neoplasms

,

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

prostatic neoplasms

,

squamous cell carcinoma

,

,

pancreatic neoplasms

,

ovarian neoplasms

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

castration-resistant prostatic neoplasms

,

intestinal diseases

,

mantle-cell lymphoma

,

,

,

myelomonocytic leukemia chronic

,

bone marrow diseases

,

sickle cell anemia

,

hypercholesterolemia

,

atherosclerosis

,

hepatocellular carcinoma

,

allergic rhinitis

,

,

,

invasive hydatidiform mole

,

stomach neoplasms

,

streptococcal infections

,

inflammatory bowel diseases

,

human influenza

,

,

waldenstrom macroglobulinemia

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

margins of excision

,

hereditary sensory and autonomic neuropathies

,

,

cardiovascular diseases

,

type 2 diabetes mellitus

,

hyperlipoproteinemia type ii

,

,

patient compliance

,

pancreatic ductal carcinoma

,

membranous glomerulonephritis

,

,

small cell lung carcinoma

,

neuroendocrine tumors

,

mucocutaneous lymph node syndrome

,

endometrial neoplasms

,

bronchiolitis obliterans syndrome

,

,

anaplastic thyroid carcinoma

,

communicable diseases

,

bacterial infections

,

gram-positive bacterial infections

,

,

smoldering multiple myeloma

,

second primary neoplasms

,

,

japanese encephalitis

,

,

central serous chorioretinopathy

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

squamous cell neoplasms

,

hodgkin disease

,

neuroendocrine carcinoma

,

type 1 diabetes mellitus

,

,

neurofibrosarcoma

,

fallopian tube neoplasms

,

coronavirus infections

,

,

,

eosinophilic esophagitis

,

,

female infertility

,

solar urticaria

,

angioid streaks

,

pseudoxanthoma elasticum

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

diffuse scleroderma

,

hemolytic anemia autoimmune

,

,

non-small-cell lung carcinoma

,

,

,

iga glomerulonephritis

,

,

meningococcal meningitis

,

,

non-hodgkin lymphoma

,

cryopyrin-associated periodic syndromes

,

,

b-cell chronic lymphocytic leukemia

,

glomerulonephritis

,

,

,

,

follicular lymphoma

,

brain neoplasms

,

lymphoid leukemia

,

paroxysmal hemoglobinuria

,

retinopathy of prematurity

,

,

urologic diseases

,

aplastic anemia

,

,

,

,

autoimmune diseases

,

juvenile arthritis

,

haemophilus infections

,

degenerative myopia

,

ankylosing spondylitis

,

polymyalgia rheumatica

,

graft vs host disease

,

psychology rejection

,

organ transplantation

,

graft rejection

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

gouty arthritis

,

osteitis deformans

,

,

allergic rhinitis seasonal

,

sjogren's syndrome

,

,

peanut hypersensitivity

,

hematologic neoplasms

,

,

neovascular glaucoma

,

giant cell arteritis

,

,

,

neoplasms by site

,

thrombocytopenic purpura idiopathic

,

chronic obstructive pulmonary disease

,

,

,

,

familial mediterranean fever

,

,

,

axial spondyloarthritis

,

,

,

,

,

,

,

thrombotic microangiopathies

,

atypical hemolytic uremic syndrome

,

choroid diseases

,

uveal neoplasms

,

,

,

pulmonary eosinophilia

,

,

,

alpha 1-antitrypsin deficiency

,

lupus nephritis

,

immune system diseases

,

male urogenital diseases

,

,

female urogenital diseases

,

female urogenital diseases and pregnancy complications

,

urogenital diseases

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

,

breast neoplasms

,

macular degeneration

,

,

,

,

,

choroidal neovascularization

,

kidney transplantation

,

vision disorders

,

meningococcal infections

,

retinal vein occlusion

,

neoplasm metastasis

,

rheumatoid arthritis

,

chronic urticaria

,

psoriatic arthritis

,

diabetic retinopathy

,

kidney diseases

,

,

liver transplantation

,

relapsing-remitting multiple sclerosis

,

chronic renal insufficiency

,

diabetes mellitus

,

spondylarthritis

,

retinal diseases

,

,

wet macular degeneration

,

geographic atrophy

,

pathologic neovascularization

,

,

polypoidal choroidal vasculopathy

,

hypersensitivity

,

renal insufficiency

,

chronic kidney failure

,

,

retinal neovascularization

,

retinal detachment

,

diabetes complications

,

thrombocytopenia

,

migraine disorders

,

,

hidradenitis suppurativa

,

,

,

food hypersensitivity

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

,

tick-borne encephalitis

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

,

,

liver cirrhosis

,

,

,

reperfusion injury

,

delayed graft function

,

,

,

,

hematopoietic stem cell transplantation

,

chronic progressive multiple sclerosis

healthy volunteers/patients

,

type 2 diabetes mellitus

,

rheumatoid arthritis

,

diabetes mellitus

,

atrial fibrillation

,

pharmacokinetics

multiple myeloma

,

,

brain neoplasms

,

,

,

,

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

follicular lymphoma

,

,

,

,

,

choroid plexus neoplasms

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

hypertrophic pyloric stenosis

,

ganglioneuroblastoma

,

phenylketonurias

,

,

myelodysplastic syndromes

,

precursor cell lymphoblastic leukemia-lymphoma

,

myeloid leukemia acute

,

,

lymphoid leukemia

,

myeloid leukemia

,

,

hematologic diseases

,

refractory anemia with excess of blasts

,

prostatic neoplasms

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

endometrial neoplasms

,

,

non-hodgkin lymphoma

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

human influenza

diabetes mellitus

,

autoimmune diseases

,

drug interactions

,

multiple sclerosis

,

,

pulmonary tuberculosis

,

,

,

,

chronic bronchitis

,

,

,

bacterial pneumonia

healthy volunteers/patients

,

rheumatoid arthritis

,

,

acute kidney injury

,

drug interactions

,

therapeutic equivalency

,

hiv seronegativity

,

nephrotic syndrome

,

,

,

biotransformation

,

pharmacokinetics

,

peripheral arterial disease

,

ventilator-associated pneumonia

,

,

wounds and injuries

,

hematopoietic stem cell transplantation

,

fontan procedure

,

,

,

,

,

,

myeloid leukemia acute

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

myeloid leukemia

,

erythroblastic leukemia acute

,

,

,

,

head and neck neoplasms

,

,

metabolic diseases

,

pulmonary fibrosis

,

hermanski-pudlak syndrome

,

oculocutaneous albinism

,

platelet storage pool deficiency

,

,

colorectal neoplasms

,

uveal neoplasms

,

,

systemic lupus erythematosus

,

congenital abnormalities

,

hematologic neoplasms

,

,

,

cardiomyopathies

,

pulmonary tuberculosis

,

liver cirrhosis

,

mucocutaneous lymph node syndrome

,

,

deglutition disorders

,

metabolic syndrome

,

breast neoplasms

,

hepatocellular carcinoma

,

liver neoplasms

,

,

chronic kidney failure

,

hyperlipoproteinemia type ii

,

vascular diseases

,

,

left ventricular hypertrophy

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

homozygous familial hypercholesterolemia

,

familial combined hyperlipidemia

,

,

hyperlipoproteinemia type iii

,

,

retinal diseases

,

pregnancy-induced hypertension

,

obstetric labor complications

,

disease progression

,

vascular dementia

,

cognitive dysfunction

,

hypercholesterolemia

,

,

cardiovascular diseases

,

,

hyperlipidemias

,

coronary artery disease

,

coronary disease

,

diabetes mellitus

,

hyperlipoproteinemias

,

,

myocardial ischemia

,

,

,

,

atherosclerosis

,

ischemic stroke

,

type 2 diabetes mellitus

,

acute coronary syndrome

,

kidney diseases

,

,

,

myocardial infarction

,

hypertriglyceridemia

,

insulin resistance

,

,

drug-related side effects and adverse reactions

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

transient ischemic attack

,

angina pectoris

,

arterial occlusive diseases

,

,

chronic renal insufficiency

,

arteriosclerosis

,

,

psychotic disorders

,

,

,

cerebral infarction

,

drug-eluting stents

,

,

postmenopausal osteoporosis

,

acute-phase reaction

,

,

prediabetic state

,

,

alzheimer disease

,

,

glucose metabolism disorders

,

lipid metabolism

,

,

stomach neoplasms

,

esophageal neoplasms

,

inferior wall myocardial infarction

,

,

,

st elevation myocardial infarction

,

unstable angina

,

malignant hyperthermia

,

prostatic neoplasms

,

postpartum depression

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

myelomonocytic leukemia chronic

,

,

myelodysplastic-myeloproliferative diseases

,

myelomonocytic leukemia juvenile

,

,

refractory anemia with excess of blasts

,

refractory anemia

,

carotid artery diseases

,

,

,

renal insufficiency

,

,

,

,

muscular diseases

Histone-arginine methyltransferase carm1

pharmacokinetics

,

chronic obstructive pulmonary disease

,

respiratory aspiration

,

positron-emission tomography

,

,

alzheimer disease

,

diagnostic imaging

,

medical sociology

,

drug interactions

,

electrocardiography

,

therapeutic equivalency

,

neuroinflammatory diseases

,

pharmacological phenomena

,

,

,

stomach neoplasms

,

hypophosphatemia

,

hematologic neoplasms

,

cystic fibrosis

,

pseudomonas infections

,

biological availability

,

castration-resistant prostatic neoplasms

,

,

non-small-cell lung carcinoma

,

breast neoplasms

,

postcoital contraception

,

ovulation inhibition

,

atrial fibrillation

,

,

,

parkinson disease

,

small cell lung carcinoma

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

cardiomyopathies

,

,

,

,

overactive urinary bladder

,

hormonal contraception

,

unplanned pregnancy

,

b-cell lymphoma

,

,

skin abnormalities

,

myocardial infarction

,

,

acquired immunodeficiency syndrome

,

magnetic resonance angiography

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

coronary disease

,

myocardial ischemia

,

interstitial lung diseases

,

thyroid neoplasms

,

thyroid diseases

,

pancreatic neoplasms

,

,

,

,

,

prostatic hyperplasia

,

,

angina pectoris

,

,

ischemic stroke

,

,

cerebral infarction

,

urologic neoplasms

,

head and neck neoplasms

,

thromboembolism

,

venous thromboembolism

,

pulmonary hypertension

,

hyperphosphatemia

,

chronic renal insufficiency

,

multiple sclerosis

,

non-hodgkin lymphoma

,

,

prostatic neoplasms

,

surgical blood loss

,

venous thrombosis

,

,

essential hypertension

,

kidney diseases

,

,

,

,

,

peripheral vascular diseases

,

postoperative hemorrhage

,

pulmonary embolism

,

cardiovascular diseases

,

,

spinal cord injuries

,

peripheral arterial disease

,

renal artery obstruction

,

,

bacterial infections

,

,

,

,

intraabdominal infections

,

,

chronic progressive multiple sclerosis

,

blood coagulation disorders

,

hormone replacement therapy

,

hyperlipidemias

,

hyperlipoproteinemias

,

choroidal neovascularization

,

,

degenerative myopia

,

pathologic neovascularization

,

,

aspiration pneumonia

,

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

metabolic bone diseases

,

premenstrual dysphoric disorder

,

diabetic nephropathies

,

,

follicular lymphoma

,

wounds and injuries

,

brain neoplasms

,

cardiovascular abnormalities

,

pathologic constriction

,

,

vascular diseases

,

memory disorders

,

carotid stenosis

,

pulmonary arterial hypertension

,

,

,

depressive disorder

,

aortic valve stenosis

,

heart valve diseases

,

ventricular outflow obstruction

,

,

abdominal abscess

,

erectile dysfunction

,

,

,

,

,

,

healthy volunteers/patients

,

renal cell carcinoma

,

,

,

atopic dermatitis

,

liver neoplasms

,

,

,

communicable diseases

,

relapsing-remitting multiple sclerosis

,

,

,

hepatocellular carcinoma

,

urinary tract infections

,

diabetes mellitus

,

coronary artery disease

,

,

type 2 diabetes mellitus

,

colorectal neoplasms

,

,

,

,

physiological sexual dysfunction

,

magnetic resonance imaging

,

neoplasm metastasis

,

acute coronary syndrome

,

tension-type headache

,

,

,

peripheral nervous system diseases

,

renal insufficiency

,

chronic bronchitis

,

,

,

,

,

respiratory tract infections

,

,

ischemic optic neuropathy

,

optic nerve diseases

,

,

,

macular degeneration

,

energy metabolism

,

,

maxillary sinusitis

,

community-acquired pneumonia

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

medicated intrauterine devices

,

,

gene expression

,

cell proliferation

,

,

,

central nervous system neoplasms

,

photoallergic dermatitis

,

phototoxic dermatitis

,

four-dimensional computed tomography

1

2

>

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